By: Preety Chaudhary
BENGALURU / November :
The trend among educated, career-oriented women of getting married late and delaying pregnancies to a later stage in life is leading to an increase in the burden of infertility where they are finding it difficult to conceive naturally. The use of assisted reproductive technologies (ART) by infertile couples is showing an increase of 5-10% every year, according to renowned Laparoscopic Surgeon and Fertility Specialist Dr. Vidya V Bhat, who is the Medical Director of RadhaKrishna Multispecialty Hospital, Bengaluru.
- The use of assisted reproductive technologies (ART) by infertile couples is showing an increase of 5-10% every year
- It is best to bear children between 25 to 33 years of age
Said Dr. Vidya V Bhat: “The recent phenomenon of reduced fertility among Indian women is caused by delayed marriages, obsession regarding one’s career, and use of modern contraceptives. Postponement of childbearing is a new behavioral change seen in Indian women, like in many other countries in the world as education levels rise. Average age of Indian urban women at their first pregnancy, and the number of pregnancies in women over 35 years of age, both have been steadily rising. As the age of women increases, the chances of them getting pregnant reduce significantly. This is due to decreased frequency of sexual intercourse, lower quality of uterus, and ageing egg cells resulting in poor-quality embryos. There is reduction in intrinsic fertility potential of egg cells after 35 years of age. The decline in fertility begins around 32 years of age and becomes rapid around 37 years of age. It is best for women to bear children between 25 to 33 years of age. Women who delay pregnancy more than this will face fertility challenges.”
Delayed childbearing impacts the health of women and children both. Said Dr. Vidya V Bhat: “Delayed pregnancies could be the reason for rise in cases of gestational diabetes among pregnant women, which sometimes even turns into type II diabetes. Women having late pregnancies have higher chances of suffering from chronic hypertension from the beginning of their pregnancy. They may also face issues during labour, such as non-progression of labour and non-descent of the fetal head. There is also increased risk of spontaneous abortion in women above 35 years of age, as well as of chromosomal anomalies being found in the baby. Obesity causes a lot of problems with respect to fertility. Women who put on a lot of weight during pregnancy may face metabolic syndrome and even recurrent loss of pregnancy.”
Many women who are single and focused on their careers in their twenties and thirties prefer to delay childbearing. They are increasingly opting for egg freezing and surrogacy as options for having a child later in life when they are ready to settle down. However, success is not guaranteed in these cases, said Dr. Vidya V Bhat. According to estimates from the Society of Assisted Reproductive Technology based on data from Indian women, the success rate of IVF is 55.6% under age 35. This declines to 40.8% in 35-37 age group, 26.8% in 38-40 age group, 12.6% in 41-42 age group and 3.9% in the age group above this. In cases of surrogacy, pregnancy rates from embryo transfer are about 53.6%.
Said Dr. Vidya V Bhat: “In life everything is important. Women should keep their personal and work lives balanced, and not treat their work life as more important than personal life. Women should keep that in mind after marriage when they decide to postpone pregnancy.”
WHO estimates the overall prevalence of primary infertility in India to be between 3.9% to 16.8%.
according to Dr. Vidya V Bhat, Laparoscopic Surgeon and Fertility Specialist and Medical Director of RadhaKrishna Multispecialty Hospital, Bengaluru.
As per the results of a large-scale survey conducted across India in 2020, about 16% of women between 20-29 years suffer from PCOS. “High levels of male sex hormones (androgens) and irregularity in the production of sugar levels in the bloodstream causing insulin resistance adversely affect a woman’s menstrual cycle. This condition can prevent the release of an egg on a regular basis, or even stop it completely, which makes it challenging for patients of PCOS to conceive easily. Sometimes it can even lead to miscarriage,” said Dr. Vidya V Bhat.
Obesity is a common finding in women with PCOS, affecting 40–80% of patients. Other causes include hormonal imbalance, stress levels, lifestyle changes, insulin resistance and metabolic defects. The treatment of PCOS-induced infertility involves monitoring ovulation, surgery for improving fertility, assisted reproductive technology, medications and weight management.
PCOS is a common but serious endocrine disorder in women of reproductive age that can lead to lifelong complications and other serious conditions. Initially, this condition is asymptomatic in young girls, progressing toward menstrual irregularities, obesity, hyper-androgenism in late puberty. Eventually it leads to insulin resistance, hypertension, type 2 diabetes, cardiovascular diseases and infertility around middle age. Yet, many women remain unaware that they are suffering from PCOS, according to the doctor.
Of late, this disease is on the rise due to environmental changes as well as lifestyle disorders. India has witnessed a spike of 30 percent in cases of PCOS in the last few years, a trend which got exacerbated due to the lifestyle changes enforced by the pandemic. Being home-bound, lack of exercise, online ordering of junk food, binge watching TV, and irregular sleep patterns have led to an increase in average weight gain among women. This, coupled with ignoring irregular or heavy menstrual cycles in the lockdown period, is driving the spike in PCOS cases.
Said Dr Vidya V Bhat: “Irregular follow-ups with the doctor during the Covid times is leading to an increase in the incidence of PCOS, especially among women who are undergoing treatment for infertility. This disorder is also linked with higher levels of circulating insulin, and there is a spike in the number of diabetic patients during the lockdown. Sedentary lifestyle and becoming a couch-potato are increasing the chances of relapse of PCOS in patients, or the disorder becoming much more severe with increased symptoms.”
PCOS can happen due to causes such as excessive consumption of saturated fat, weight gain, inflammation, chemicals and hormonal imbalance. Lifestyle management is very important for PCOS patients, including regulated diet, physical exercise and management of blood sugar and hypertension.